This two-volume set LNAI 16121-16122 constitutes the proceedings of the 24th EPIA Conference on Progress in Artificial Intelligence, EPIA 2025, held in Faro, Portugal, during October 1&3, 2025.

The 76 full papers included in these proceedings were carefully reviewed and selected from 158 submissions. They were organized in topical sections as follows:

Part I: Artificial Intelligence in Medicine (AIM); AI for Architecture, Engineering and Conservation (AI4AEC); Knowledge Discovery and Business Intelligence (KDBI); Generative AI: Foundations and Applications (GenAI); Artificial Intelligence: Theory, Methods, and Applications (AITMA); Ethics and Responsibility in AI (ERAI).

Part II: Artificial Intelligence for Industry and Societies (AI4IS); Artificial Intelligence and Law (AIL); Artificial Intelligence and IoT in Agriculture (AIoTA); Artificial Intelligence in Transportation Systems (AITS); Natural Language Processing, Text Mining and Applications (NLP-TeMA); Ambient Intelligence and Affective Environments (AmIA); AI and Creativity (AIC); Artificial Intelligence in Power and Energy Systems (AIPES); Fuzzy Data Analysis and Applications (FDA).